Quinone
redox-active ring compounds that shuttle electrons.
3 compounds · filter the full catalogue by this class
- Coenzyme Q10Quinone
Coenzyme Q10 (CoQ10) is part of the mitochondrial energy chain and one of the most widely used supplements. Its best evidence is in chronic heart failure. There, the Q-SYMBIO trial found fewer major cardiovascular events and deaths over two years. For statin muscle pain, migraine and blood pressure, the results are mixed or modest.
Human RCTs - PQQQuinone
PQQ (pyrroloquinoline quinone) is a redox cofactor first found in bacteria. Mammals do not make it but take in trace amounts from food. In cells it switches on mitochondrial biogenesis through the PGC-1α pathway. In humans, small 12-week trials of PQQ disodium salt reported better memory and attention scores.
Human RCTs - UbiquinolQuinone
Ubiquinol is the reduced, electron-carrying form of coenzyme-q10, sold as a better-absorbed version. One small study found it raised blood CoQ10 more than ubiquinone. A randomised crossover study in older adults found no significant difference. Its most notable trial is in multiple-system atrophy, where high doses improved a motor score.
Human RCTs